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Hebrew: 'ezob; LXX [Septuagint]: hyssopos)
Hyssop is first mentioned in Exodus 12:22 in connection with the institution of the Passover. We find it afterwards mentioned in Leviticus 14:4, 6, 52; Numbers 19:6, 18; Heb. 9:19. It is spoken of as a plant “springing out of the wall” (1 Kings 4:33).
Many conjectures have been formed as to what this plant really was. Some contend that it was a species of marjoram (origanum), six species of which are found in Israel. Others with more probability think that it was the caper plant, the Capparis spinosa of Linnaeus. This plant grew in Egypt, in the desert of Sinai, and in Israel. It was capable of producing a stem three or four feet in length (Matthew 27:48; Mark 15:36. Compare John 19:29).