ChristianAnswers.Net WebBible Encyclopedia
Meaning: double fruitfulness (“for God had made him fruitful in the land of his affliction”)
The first incident recorded regarding him is his being placed, along with his brother Manasseh, before their grandfather, Jacob, that he might bless them (48:10; compare 27:1). The intention of Joseph was that the right hand of the aged patriarch should be placed on the head of the elder of the two; but Jacob set Ephraim the younger before his brother, “guiding his hands wittingly.”
Before Joseph’s death, Ephraim’s family had reached the third generation (Gen. 50:23).