Properly what is in front of one, or a country that is before or in front of another; the rendering of the word kedem.
In pointing out the quarters, a Hebrew always looked with his face toward the east.
The word kedem is used when the four quarters of the world are described (Genesis 13:14; 28:14); and mizrah when the east only is distinguished from the west (Josh. 11:3; Psalm 50:1; 103:12, etc.).
In Genesis 25:6 “eastward” is literally “unto the land of kedem;” i.e., the lands lying east of Israel, namely, Arabia, Mesopotamia, etc.