Will & Grace 1998-2020 (246 episodes)
Show Synopsis: (from the producer) Will Truman (Eric McCormack) and Grace Adler (Debra Messing) are best friends and neighbors in this adult comedy about two people who seem perfect for each other but can never actually find romance together because Will is gay and Grace is straight…
On the show, Will is a successful Manhattan lawyer—likable, handsome and charming—who recently ended a long-term relationship. Likewise, Grace is a beautiful, self-employed interior decorator. They both love French films, poker night with the guys and the home version of "The $10,000 Pyramid." Will and Grace have been friends for a long time, and though they're both looking for love, they long ago accepted the fact that there will be no romance between them. As a result, they face lifes ups-and-downs together, knowing they will always have each other to lean on.